That gave Napoli four RBIs for the game, including a sacrifice fly in the seventh that tied it 3-3, after he singled in Los Angeles' second run in the second inning.

While the homer gave Los Angeles the win, manager Mike Scioscia seemed just as impressed by Napoli's two earlier RBIs.

"I really liked the sacrifice fly. He shortened up and hit a really tough pitch," Scioscia said. "And on his (broken-bat single), he got jammed but got just enough of it to get it over the infield."

Jose Arredondo (8-2) pitched a perfect ninth for the victory.

Although they wrapped up the AL West on Wednesday, the Angels still want to secure home-field advantage throughout the AL playoffs. Their 90-57 record is baseball's best.

"Just because we've clinched doesn't mean we're going to lie down," Napoli said. "We're all excited, but we've still got a lot of baseball to play."

The Angels' Juan Rivera led off the seventh with a double against Ryan Rowland-Smith, went to third on Quinlan's groundout and scored the tying run on Napoli's sacrifice fly.

Los Angeles closer Francisco Rodriguez, not needed this time, still has 15 games remaining to try to rewrite the major league single-season saves record. He got his 57th in Thursday night's 7-4 win over Seattle to match Bobby Thigpen's record set in 1990. Rodriguez had moved within one of the mark when he pitched the ninth of the Angels' AL West-clinching victory over the New York Yankees the previous day.

Angels right fielder Vladimir Guerrero left the game after four innings because of soreness in his right knee. Scioscia said he took him out as a precaution and may let him rest for a couple of days.

Adrian Beltre had two hits and drove in two runs for Seattle as he extended his hitting streak to 15 games, the longest active streak in the majors.

After Beltre doubled home a run in the first, Quinlan's RBI triple and a Napoli's run-scoring single gave Los Angeles a 2-1 lead in the second.

The Mariners moved out front with a pair of runs off Joe Saunders in the fifth, on two-out RBI singles by Raul Ibanez and Beltre.